A no-flush, core-cooling technique for successful cardiopulmonary preservation in heart-lung transplantation
نویسندگان
چکیده
منابع مشابه
Retrograde flush following topical cooling is superior to preserve the non-heart-beating donor lung.
OBJECTIVE The use of non-heart-beating donors (NHBD) has been propagated as an alternative to overcome the scarcity of pulmonary grafts. Formation of microthrombi after circulatory arrest, however, is a major concern for the development of reperfusion injury. We looked at the effect and the best route of pulmonary flush following topical cooling in NHBD. METHODS Non-heparinized pigs were sacr...
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Background Ovarian tissue cryopreservation is an option for patients who require immediate gonagonadotoxic treatment of cancers. when there is insufficient time to conduct ovulation induction This procedure can be used in patients with genetic mutations with a high risk for premature ovarian failure.This strategy is the only option for fertility preservation in prepubertal girls or in women who...
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A shortage of donor organs in clinical transplantation prompted us to study whether resuscitated dead hearts could be utilized for successful orthotopic heart transplantation. After 60 min of hypoxic cardiac arrest, one group of canine hearts was resuscitated (Res group, n = 6). The other group was harvested directly (Non-Res group, n = 6). In the Res group, cardiopulmonary bypass was utilized ...
متن کاملCritical time window for intra-arrest cooling with cold saline flush in a dog model of cardiopulmonary resuscitation.
BACKGROUND Mild hypothermia improves outcome when induced after cardiac arrest in humans. Recent studies in both dogs and mice suggest that induction of mild hypothermia during cardiopulmonary resuscitation (CPR) greatly enhances its efficacy. In this study, we evaluate the time window for the beneficial effect of intra-arrest cooling in the setting of prolonged CPR in a clinically relevant lar...
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The exercise capacity and cardiopulmonary response to progressive dynamic exercise of eight healthy recipients of heart-lung transplants were compared with those of matched recipients of orthotopic cardiac transplants and normal controls. In both transplant groups the maximum workloads were lower than that in the normal group. The transplant recipients had higher pre-exercise heart rates and lo...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 1987
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(19)36155-0